Berberis Formula 90 Veggie Caps

Combination of berberine extracts from natural plant sources
• Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as dyspepsia, and as a mild laxative
• Includes goldenseal root extract, barberry root and stem extract, barberry root bark, Oregon grape root extract, and Oregon grape root

Berberis Formula is a blend of barberry, goldenseal and Oregon grape extracts that are traditionally used in Herbal Medicine to help maintain gastrointestinal health. The main bioactive ingredient in these extracts is berberine.^1,2 Recent research demonstrates that berberine inhibits bacterial attachment to the gastric mucosa.³ Berberine also mediates the transport of ions and water across intestinal epithelial cells.³ It helps maintain the balance between electrolytes and water, resulting in an anti-diarrheal effect.3 Berberine can increase the expression of the Na+; H+ exchanger and aquaporin,² which help enhance the absorption of sodium and water, respectively.^3,4 Berberine also promotes proper intestinal epithelial tight junction formation, and decreases the permeability of these cells to promote appropriate gastrointestinal barrier function.⁵ During low contractile states, berberine stimulates the jejunum through the activation of muscarinic receptors, resulting in increased intestinal motility, and a mild laxative effect._⁶

EACH CAPSULE CONTAINS: Barberry (Berberis vulgaris) Root and Stem Extract (4:1) . . 200mg 800 mg Dried Equivalent Oregon Grape (Mahonia aquifolium) Root Extract (4:1) (Mahonia aquifolium) (4:1) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200mg 800 mg Dried Equivalent Goldenseal (Hydrastis canadensis) Root Std. Extract (10:1) (5% Alkaloids) (10:1) (5 % d’alcaloïdes) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50mg 500 mg Dried Equivalent Barberry (Berberis vulgaris) Root Bark . . . . . . . . . . . . . 25mg Oregon Grape (Mahonia aquifolium) Root . . . . . . 25mg Non-Medicinal Ingredients: Hypromellose, cellulose, silica

Recommended Dose: Adults (19 years and older): Take one capsule two times daily with meals or as recommended by your healthcare practitioner. May take up to one week to produce beneficial effects.

Risk Information: If you are pregnant or breastfeeding, do not use. If symptoms persist or worsen, consult your healthcare practitioner. If you have a kidney disorder, blood pressure problems, heart or respiratory condition, consult your healthcare practitioner prior to use. Consumption with alcohol, other medications and/or natural health products with sedative properties is not recommended. Do not exceed the recommended dose. Discontinue use and consult your healthcare practitioner if the following symptoms occur: nausea, vomiting, drop in blood pressure and/or difficulty breathing. High dosages of berberine can depress respiration, stimulate intestinal smooth muscle and reduce bronchial constriction.