ULTIMATE GLUCOSAMINE is a powder consisting of 100% pure N-acetylglucosamine. This unique formulation contains no additives, salts, preservatives, coloring agents, gluten, lactose or yeast. It dissolves readily and can be added to any hot or cold beverage as a mild sweetener.
N-acetylglucosamine is a major component of hyaluronan, a substance that functions as a lubricant in joints. It is important in the growth and repair of joint cartilage. It has also been shown to repair joint damage in experimental models of osteoarthritis1,4.
In addition, it has been shown to have anti-inflammatory properties in vitro. N-acetylglucosamine has been administered to children2 in amounts up to 6 grams per day for up to 2 years without any reported adverse effects.
Lack of adverse effects is probably explained by the fact that N-acetylglucosamine is a natural and important nutritional substance. Human breast milk3 contains as much as 1.5 grams per liter of milk and is the second most abundant sugar after lactose.
References
1 Shikhman AR, Amiel D, D’Lima D, Hwang SB, Hu C, Xu A, Hashimoto S, Kobayashi K, Sasho T, Lotz MK. Chondroprotective activity of N-acetylglucosamine in rabbits with experimental osteoarthritis. Ann Rheum Dis. 2005 Jan;64(1):89-94.
2 Salvatore S, Heuschkel R, Tomlin S, Davies SE, Edwards S, Walker-Smith JA, French I, Murch SH. A pilot study of N-acetyl glucosamine, a nutritional substrate for glycosaminoglycan synthesis, in paediatric chronic inflammatory bowel disease. Aliment Pharmacol Ther. 2000 Dec;14(12):1567-79.
3 Miller JB, Bull S, Miller J, McVeagh P. The oligosaccharide composition of human milk: temporal and individual variations in monosaccharide components. J Pediatr Gastroenterol Nutr. 1994 Nov;19(4):371-6.
4 Chang N, Lin YT, Lin CC, et al. The repair of full-thickness articular cartilage defect using intra-articular administration of N-acrtyl-D-glucosamine in the rabbit knee: randomized controlled tial. BioMed Eng OnLine 2015 14:105.
How To Take It?
We recommend that your patients add 1 level teaspoon of ULTIMATE GLUCOSAMINE to any hot or cold drink including tea, coffee, juice, milk or soda. The once-a-day powder format can easily be adapted to their daily routine:
For a relaxing bedtime drink, add 1 teaspoon to a cup of camomile tea.
Add 1 teaspoon to their morning ritual, a smoothie or a cup of coffee.
Sprinkle 1 teaspoon over hot or cold cereal.
After any physical activity, add 1 teaspoon to a favorite energy drink.
Usual dose
One level teaspoon
Most people take 1 level teaspoon (5 mL), or about 2 grams at a time. Others prefer to use more, especially when they first start taking ULTIMATE GLUCOSAMINE. Since the substance has no known toxicity, 2 to 3 teaspoons per day can be taken without any side effects.
The maximum dosage of N-acetylglucosamine has not been established because it is a food substance. However, here are some facts to guide your advice to patients:
