What is Ultimate Glucosamine?

ULTIMATE GLUCOSAMINE is a powder consisting of 100% pure N-acetylglucosamine. This unique formulation contains no additives, salts, preservatives, coloring agents, gluten, lactose or yeast. It dissolves readily and can be added to any hot or cold beverage as a mild sweetener.

N-acetylglucosamine is a major component of hyaluronan, a substance that functions as a lubricant in joints. It is important in the growth and repair of joint cartilage. It has also been shown to repair joint damage in experimental models of osteoarthritis^1,4.

In addition, it has been shown to have anti-inflammatory properties in vitro. N-acetylglucosamine has been administered to children² in amounts up to 6 grams per day for up to 2 years without any reported adverse effects.

Lack of adverse effects is probably explained by the fact that N-acetylglucosamine is a natural and important nutritional substance. Human breast milk³ contains as much as 1.5 grams per liter of milk and is the second most abundant sugar after lactose.

References

1 Shikhman AR, Amiel D, D’Lima D, Hwang SB, Hu C, Xu A, Hashimoto S, Kobayashi K, Sasho T, Lotz MK. Chondroprotective activity of N-acetylglucosamine in rabbits with experimental osteoarthritis. Ann Rheum Dis. 2005 Jan;64(1):89-94.

2 Salvatore S, Heuschkel R, Tomlin S, Davies SE, Edwards S, Walker-Smith JA, French I, Murch SH. A pilot study of N-acetyl glucosamine, a nutritional substrate for glycosaminoglycan synthesis, in paediatric chronic inflammatory bowel disease. Aliment Pharmacol Ther. 2000 Dec;14(12):1567-79.

3 Miller JB, Bull S, Miller J, McVeagh P. The oligosaccharide composition of human milk: temporal and individual variations in monosaccharide components. J Pediatr Gastroenterol Nutr. 1994 Nov;19(4):371-6.

4 Chang N, Lin YT, Lin CC, et al. The repair of full-thickness articular cartilage defect using intra-articular administration of N-acrtyl-D-glucosamine in the rabbit knee: randomized controlled tial. BioMed Eng OnLine 2015 14:105.

How To Take It?

We recommend that your patients add 1 level teaspoon of ULTIMATE GLUCOSAMINE to any hot or cold drink including tea, coffee, juice, milk or soda. The once-a-day powder format can easily be adapted to their daily routine:

For a relaxing bedtime drink, add 1 teaspoon to a cup of camomile tea.
Add 1 teaspoon to their morning ritual, a smoothie or a cup of coffee.
Sprinkle 1 teaspoon over hot or cold cereal.
After any physical activity, add 1 teaspoon to a favorite energy drink.

Usual dose

One level teaspoon

Most people take 1 level teaspoon (5 mL), or about 2 grams at a time. Others prefer to use more, especially when they first start taking ULTIMATE GLUCOSAMINE. Since the substance has no known toxicity, 2 to 3 teaspoons per day can be taken without any side effects.

The maximum dosage of N-acetylglucosamine has not been established because it is a food substance. However, here are some facts to guide your advice to patients:

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