Agaricus Bisporus SAPis a hot water–extract from white button mushroom (WBM;Agaricus bisporus), the most commonly consumed mushroom in North America and most Western countries.A. bisporusconstitutes of a significant amount of vitamin D precursor ergosterol, dietary fibres, and antioxidants including vitamins C, B12, folates, and polyphenols. In addition, lectins fromA. bisporusexert various beneficial effects including their role in improving the chemotherapeutic efficacy of cancer treatments, and their ability in inhibiting colon cancer–cell proliferation and enhancing the cellular antioxidant defense mechanisms. As a potent aromatase inhibitor and immunomodulatory agent in increasing natural killer-cell activity and promoting adaptive immune responses,A. bisporusextracts have gained recent attention for their potential value in breast and prostate cancer support. Also, studies support the application ofA. bisporusextracts in type 2 diabetes, metabolic syndrome, cholesterol management, and cardiovascular disease (CVD). Earlystage preclinical evidence suggests the physiological benefits ofA. bisporusin improving working memory and balance during aging.Agaricus Bisporus SAPcan be used as an adjunctive support in the treatments of cancers, diabetes, and cholesterol management, as well as in CVD risk alleviation.
